Science Questions and Answers
Science Questions and Answers

Science Questions and Answers

@proteomicsqaquesitons

Sialic acids are negatively charged monosaccharides, what are found on the non-reducing termini of glycans. The key role in product stability and efficacy, thus, sialic acids are often defined in glycoprotein therapeutic products. There exist two most common sialic acids in biopharmaceuticals, the one is N-acetyl-neuraminic acid (Neu5Ac) and the other one is N-glycolyl-neuraminic acid (Neu5Gc). The sialic acid mentioned above are both important to the firmness and 3D conformation of glycoproteins, they are involved in many biological interactions. structure of siliac acid https://www.creative-proteomic....s.com/pronalyse/sili

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Glycosylation, the process of attaching glycans to proteins or other organic molecules, is one of the most common post-translational modifications (PTMs). Glycans are highly branched carbohydrate structures, consisting of monosaccharide sugars, such as fucose, galactose, manose, sialic acid, and N-acetylglucosamine. Due to the complexity and diversity of composition and structure of glycans, and the site of glycan attachment, glycosylation may affect product stability, immunogenicity, serum clearance, pharmacokinetics, and anti-inflammatory activity. Therefore, glycosylation is a Critical Quality Attribute (CQA) that must be present

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Creative Proteomics has deep industry and business process expertise, global resources, and a good reputation in providing contract services specialized for metabolomics. We aim to provide high-quality, personalized services and reliable data to support our global customers. Our professional bioinformatics team provides a broader perspective, supporting data interpretation that enables our clients to understand biological issues in-depth and promote the development of science that makes a difference in people's lives. dihydroxyacetone phosphate assay https://metabolomics.creative-....proteomics.com/dihyd

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Biotin (Vitamin B7) is a vitamin essential for the maintenance of normal physiological functions in the animal organism. It plays an important role in the metabolism of glucose, amino acids and fatty acids in mammals as a component of four carboxylase coenzymes. There are five biotin-dependent carboxylases: methylcrotonyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase and two forms of acetyl-CoA carboxylase. biotin and metabolism https://metabolomics.creative-....proteomics.com/bioti

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A saturated fatty acid has no double bonds between the carbons. It has the maximum possible number of hydrogen atoms attached to every carbon atom. Therefore, it is said to be "saturated" with hydrogen atoms, and all of the carbons are attached to each other with single bonds; saturated and unsaturated fatty acids https://lipidomics.creative-pr....oteomics.com/saturat

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Saturated Fatty Acids - Lipidomics|Creative Proteomics

High consumption of saturated fatty acids has been shown to play negative roles in human health. A lowered intake of saturated fatty acids has commonly been indicated for improved cardiovascular health. Creative Proteomics provides comprehensive satu